
Human-in-the-Loop LLM Framework Boosts Detection of Skin Immune Reactions in Clinical Notes
A new retrieval-augmented, multi-agent LLM framework with human-in-the-loop oversight improved detection of cutaneous immune-related adverse events from clinical notes, boosting accuracy (F1: 0.88 vs 0.77) and inter-rater agreement (kappa: 0.82 vs 0.50) while cutting review time by half.





















